Altered heat stress response following streptozotocin-induced diabetes
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چکیده
منابع مشابه
The Ultrastructural Changes of the Sertoli and Leydig Cells Following Streptozotocin Induced Diabetes
Objective(s) This investigation was conducted to evaluate the effects of diabetes on the structure and function of testicular tissue. Materials and Methods Diabetes was induced in male adult rats by a single intraperitoneal injection of streptozotocin. Body and testicular weight, hormonal analyses, histological and ultrastructural analyses were measured. Results The body and testicular we...
متن کاملT-cell Tolerance Following Bacterial Glutamic Acid Decarboxylase (GAD) Feeding in Streptozotocin-induced Diabetes
Background: Autoimmune type 1 diabetes mellitus is caused by T-cell mediated immune destruction of the insulin-producing β-cell in pancreatic islets of Langerhans. Specificity of the auto-antibodies and of the auto-reactive T-cells has been investigated, in which several auto-antigens were proposed. Objective: To determine whether glutamic acid decarboxylase (GAD) feeding would induce oral tol...
متن کاملFactors influencing the altered thermogenic response of rat brown adipose tissue in streptozotocin-diabetes.
1. Adipocytes were isolated from the interscapular brown fat of male rats maintained at 21 degrees C. These animals were controls, streptozotocin-diabetics or 2-day insulin-treated diabetics. 2. With adipocytes from diabetic animals, maximum rates of noradrenaline-stimulated O2 uptake were decreased by 58%, and the Bmax. of [3H]GDP binding to mitochondria was decreased by 55%. Insulin administr...
متن کاملInsulin Restores an Altered Corneal Epithelium Circadian Rhythm in Mice with Streptozotocin-induced Type 1 Diabetes
The mechanisms of corneal epithelial lesions and delayed wound repair, as well as their association with diabetes mellitus, are critical issues for clinical ophthalmologists. To test whether the diabetic condition alters the circadian rhythm in a mouse cornea and whether insulin can synchronise the corneal clock, we studied the effects of streptozotocin-induced diabetes on the mitosis of epithe...
متن کاملAltered glycogen metabolism in the submandibular and parotid salivary glands of rats with streptozotocin-induced diabetes.
Experimental animal models of diabetes induced either by alloxan or streptozotocin have been used to study aspects of the pathophysiology of this disease. The purpose of this study was to examine the metabolism of glycogen in the submandibular and parotid salivary glands of diabetic rats. Diabetes was induced by an intraperitoneal injection of streptozotocin. Eight weeks after the induction of ...
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ژورنال
عنوان ژورنال: Cell Stress & Chaperones
سال: 2007
ISSN: 1355-8145,1466-1268
DOI: 10.1379/csc-292.1